Murine Basophils Are Mature and Activated Upon Arrival In the Popliteal Lymph Node After Papain Footpad Injection

Basophils have been shown to present antigen and may drive Th2 lymphocyte development upon exposure to certain allergens and helminths yet the location of activation, trigger for maturation, and survival kinetics are not well characterized.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB177-AB177
Main Authors: Liu, A.Y, Dwyer, D.F, Jones, T.G, Gurish, M.F
Format: Article
Language:English
Subjects:
Allergy and Immunology
Medical research
Online Access:Get full text
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Description
Summary:Basophils have been shown to present antigen and may drive Th2 lymphocyte development upon exposure to certain allergens and helminths yet the location of activation, trigger for maturation, and survival kinetics are not well characterized.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.694