Impaired TH17 Cell Production In Patients With Chronic Candida albicans Infections

CMC patients (n = 12) and HIES patients with STAT3 mutations in the DNA-binding domain (n = 26) showed normal tyrosine phosphorylation (Y705) of STAT3 in response to IL-6.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB55-AB55
Main Authors: Renner, E.D, Kusuma, T, Jansson, A, Sawalle, J, Schimke, L, Reichenbach, J, Roesler, J, Borte, M, Torgerson, T, Ochs, H.D, Belohradsky, B.H, Rothenfusser, S, Albert, M
Format: Article
Language:English
Subjects:
Allergy and Immunology
Fungal infections
Mutation
Phosphorylation
Online Access:Get full text
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Description
Summary:CMC patients (n = 12) and HIES patients with STAT3 mutations in the DNA-binding domain (n = 26) showed normal tyrosine phosphorylation (Y705) of STAT3 in response to IL-6.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.251