IL-4 Bypasses Innate Immune Signals in Inhalational Priming

Co-administration of IL-4 with antigen induces distinct phenotypical changes of lung and lymph node DCs and cocultures indicate that IL-4 induces sufficient migration and maturation of DCs to prime T cells.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2007, Vol.119 (1), p.S128-S128
Main Authors: Dittrich, A, Bottomly, K
Format: Article
Language:English
Subjects:
Allergy and Immunology
Cell growth
Immune system
Lymphocytes
Medical research
Online Access:Get full text
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Description
Summary:Co-administration of IL-4 with antigen induces distinct phenotypical changes of lung and lymph node DCs and cocultures indicate that IL-4 induces sufficient migration and maturation of DCs to prime T cells.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2006.11.487