Monocyte Chemotactic Protein-4 (MCP-4; CCL-13) and the CC chemokine Receptor 3 (CCR3) in Sputum of Asthmatic Children

Percentage of sputum total cells, eosinophils and lymphocytes expressing MCP-4 and/or CCR3 were significantly higher during asthma exacerbation than controls and they were negatively correlated to peak expiratory flow rate, whereas percentage of expressing monocytes was not.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2007, Vol.119 (1), p.S72-S72
Main Authors: El-Gamal, Y.M, Heshmat, N.M, Awwad, K.S, Ezzat, M.H.M, Abd Al-Aziz, M.M, El-Gabbas, Z.M
Format: Article
Language:English
Subjects:
Allergy and Immunology
Asthma
Chemokines
Leukocytes
Lymphocytes
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Description
Summary:Percentage of sputum total cells, eosinophils and lymphocytes expressing MCP-4 and/or CCR3 were significantly higher during asthma exacerbation than controls and they were negatively correlated to peak expiratory flow rate, whereas percentage of expressing monocytes was not.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2006.11.304