A Mite Antigen, Der P1, Activates Dendritic Cells (DCs) and Stimulates Th2 Polarization through a Toll-like Receptor (TLR)-4 Pathway

Rationale Exposure to mite is implicated in the development and exacerbation of asthma and other allergic diseases. [...]we investigated whether a mite allergen, Der p 1, directly stimulates DCs and promotes allergic responses.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S198-S198
Main Authors: Dave, S.A, Yoon, J, Wada, K, Kobayashi, T, Naseri, M, Kita, H
Format: Article
Language:English
Subjects:
Allergy and Immunology
Cytokines
Lymphocytes
Rodents
Online Access:Get full text
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Description
Summary:Rationale Exposure to mite is implicated in the development and exacerbation of asthma and other allergic diseases. [...]we investigated whether a mite allergen, Der p 1, directly stimulates DCs and promotes allergic responses.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.735