Endotoxin attacks the cardiovascular system: Black death at the tollgateEditorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology

[...]inhibiting normal innate immune mechanisms in low-risk patients may have deleterious effects. [...]oxidative stress in sepsis involves several reactive oxygen species (e.g., superoxide, hydrogen peroxide, hydroxyl radicals) and antioxidative defense mechanisms (e.g., superoxide dismutase, catal...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2003-11, Vol.42 (9), p.1663
Main Author: Lew, Wilbur YW
Format: Article
Language:English
Subjects:
Antioxidants
Bacteria
Bacterial infections
Cardiology
Cardiovascular disease
Clinical trials
Fatalities
Mortality
Nitric oxide
Oxidative stress
Sepsis
Signal transduction
Studies
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Summary:[...]inhibiting normal innate immune mechanisms in low-risk patients may have deleterious effects. [...]oxidative stress in sepsis involves several reactive oxygen species (e.g., superoxide, hydrogen peroxide, hydroxyl radicals) and antioxidative defense mechanisms (e.g., superoxide dismutase, catalase, vitamins C and E, and glutathione) (19). [...]impairments were measured 4 h after LPS exposure in healthy subjects.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2003.08.006