Phase Analysis of Gated Myocardial Perfusion Single-Photon Emission Computed Tomography Compared With Tissue Doppler Imaging for the Assessment of Left Ventricular Dyssynchrony

Phase Analysis of Gated Myocardial Perfusion Single-Photon Emission Computed Tomography Compared With Tissue Doppler Imaging for the Assessment of Left Ventricular Dyssynchrony Maureen M. Henneman, Ji Chen, Claudia Ypenburg, Petra Dibbets, Gabe B. Bleeker, Eric Boersma, Marcel P. Stokkel, Ernst E. v...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2007-04, Vol.49 (16), p.1708-1714
Main Authors: Henneman, Maureen M., MD, Chen, Ji, PhD, Ypenburg, Claudia, MD, Dibbets, Petra, MSc, Bleeker, Gabe B., MD, Boersma, Eric, PhD, Stokkel, Marcel P., MD, PhD, van der Wall, Ernst E., MD, PhD, Garcia, Ernest V., PhD, Bax, Jeroen J., MD, PhD
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Cardiac Output, Low - therapy
Cardiac Pacing, Artificial
Cardiology
Cardiology. Vascular system
Cardiomyopathy
Cardiovascular
Confidence intervals
Female
Heart attacks
Heart failure
Humans
Internal Medicine
Male
Medical imaging
Medical sciences
Middle Aged
Myocardium
Predictive Value of Tests
Sensitivity and Specificity
Studies
Tomography, Emission-Computed, Single-Photon
Ultrasonography, Doppler
Ventricular Dysfunction, Left - diagnostic imaging
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Summary:Phase Analysis of Gated Myocardial Perfusion Single-Photon Emission Computed Tomography Compared With Tissue Doppler Imaging for the Assessment of Left Ventricular Dyssynchrony Maureen M. Henneman, Ji Chen, Claudia Ypenburg, Petra Dibbets, Gabe B. Bleeker, Eric Boersma, Marcel P. Stokkel, Ernst E. van der Wall, Ernest V. Garcia, Jeroen J. Bax It has been suggested that left ventricular (LV) dyssynchrony is an important predictor of response to cardiac resynchronization therapy. Left ventricular dyssynchrony is predominantly assessed with tissue Doppler imaging (TDI); however, information on LV dyssynchrony can also be provided by gated myocardial perfusion single-photon emission computed tomography (GMPS) with phase analysis. In 75 patients with heart failure, TDI and GMPS were performed as part of clinical screening for eligibility for cardiac resynchronization therapy and compared for assessment of LV dyssynchrony. Results demonstrate that histogram bandwidth and phase SD with phase analysis correlated best with LV dyssynchrony on TDI, suggesting that these parameters might be preferred for assessment of LV dyssynchrony with GMPS.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2007.01.063