A New Adenosine-Independent Index of Stenosis Severity

Assuming that the resistance to flow during the wave-free period is equal to the average resistance during maximal hyperemia neglects the role of the coronary microvasculature in controlling blood flow. The wave analysis theory largely explains the flow pattern in the coronary arteries, but not the...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2012-05, Vol.59 (21), p.1915-1915
Main Authors: Finet, Gérard, MD, PhD, Rioufol, Gilles, MD, PhD
Format: Article
Language:English
Subjects:
Adenosine
Cardiology
Cardiovascular
Internal Medicine
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Summary:Assuming that the resistance to flow during the wave-free period is equal to the average resistance during maximal hyperemia neglects the role of the coronary microvasculature in controlling blood flow. The wave analysis theory largely explains the flow pattern in the coronary arteries, but not the absolute level of flow, and should not justify the calculation of hyperemic flow parameters from nonhyperemic pressure measurements.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2012.01.048