TCT-10 Efficacy of renal denervation is positively impacted by longitudinal treatments

Treatment Description Circumferential coverage (%) Average length coverage (%) Average NEPI (ng/g) NEPI reduction (% vs. control) Percentage of affected nerves Single V2 treatment One treatment per artery (each electrode = 4 mm long and 2.5 mm wide) 95% 60% 322±331 -46% 40%±11 V2 treatments of full...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2012-10, Vol.60 (17), p.B3-B3
Main Author: Mazor, Meital
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular
Electrodes
Internal Medicine
Medical treatment
Veins & arteries
Online Access:Get full text
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Summary:Treatment Description Circumferential coverage (%) Average length coverage (%) Average NEPI (ng/g) NEPI reduction (% vs. control) Percentage of affected nerves Single V2 treatment One treatment per artery (each electrode = 4 mm long and 2.5 mm wide) 95% 60% 322±331 -46% 40%±11 V2 treatments of full artery length Up to 2 treatments in order to treat the entire length of the artery (proximal treatment could be partial, with only a few RF electrodes activated) 95% 100% 132±191 -78% 58%±17 Single V2 treatment using balloon with horizontal RF electrodes Electrodes were positioned in an horizontal pattern in order to increase circumferential coverage (each electrode is 2.5 mm long and 4 mm wide) 130% 60% 356±321 -41% 37%±14 Surgical denervation Adventitia was separated along the entire length of the artery and renal nerves removed 100% 100% 154±285 -75% NA Untreated Sham control Interventional procedure, without renal denervation treatment. 0% 0% 601±61 0% 0%
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2012.08.015