Basis function approach to the evaluation of the limits of applicability of graphical methods in the analysis of very-high-affinity PET ligands

Along with the model order, the method provides estimates of binding potential (BP), relative target/reference plasma clearance rate ratio (R1), and normalized uptake rate constant (KI/VD) for PET tracers.

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Bibliographic Details
Published in:NeuroImage (Orlando, Fla.) Fla.), 2006, Vol.31, p.T70-T70
Main Authors: Graner, John L., Holden, J.E., Converse, A.K., Flores, L.G., Sossi, V.
Format: Article
Language:English
Subjects:
Estimates
Kinetics
Ligands
Methods
Online Access:Get full text
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Description
Summary:Along with the model order, the method provides estimates of binding potential (BP), relative target/reference plasma clearance rate ratio (R1), and normalized uptake rate constant (KI/VD) for PET tracers.
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2006.04.060