Relationship between prefrontal cognitive functions and dopaminergic transmission: A [18F]-fluoro- l-DOPA PET study

Introduction: Several dopaminergic pathways have been linked to functions as extrapyramidal motor control, motivation, and cognition. [...]among other functions, dopaminergic transmission influences cognitive processes like sustained attention, working memory, conflict control, and decision-making....

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Published in:NeuroImage (Orlando, Fla.) Fla.), 2006, Vol.31, p.T172-T172
Main Authors: Vernaleken, Ingo, Kumakura, Y., Buchholz, H.-G., Siessmeier, T., Bartenstein, P., Cumming, P., Gründer, G.
Format: Article
Language:English
Subjects:
Brain
Dopamine
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Summary:Introduction: Several dopaminergic pathways have been linked to functions as extrapyramidal motor control, motivation, and cognition. [...]among other functions, dopaminergic transmission influences cognitive processes like sustained attention, working memory, conflict control, and decision-making. Results: At baseline, we found significant positive correlations between the magnitude of Kinapp in caudate nucleus, putamen, and midbrain with performance of the TMT-B, CPT-M, and the Stroop Test.
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2006.04.155