Effects of the Synthetic Estrogen 17[alpha]-Ethinylestradiol on Aromatase Expression, Reproductive Behavior and Sperm Quality in the Fish Jenynsia multidentata

The synthetic estrogen 17[alpha]-ethynylestradiol (EE^sub 2^) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE^sub 2^ exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Se...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 2014-05, Vol.92 (5), p.579
Main Authors: Roggio, M A, Guyón, N F, Hued, A C, Amé, M V, Valdés, M E, Giojalas, L C, Wunderlin, D A, Bistoni, M A
Format: Article
Language:English
Subjects:
Animal populations
Effluents
Estrogens
Fish
Sewage
Sexual behavior
Sperm
Toxicity
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Summary:The synthetic estrogen 17[alpha]-ethynylestradiol (EE^sub 2^) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE^sub 2^ exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Sexual behavior, brain and gonadal aromatase expression as well as sperm quality were evaluated. The brain aromatase expression, reproductive behavior, spermatozoa viability and gonadosomatic index were sensitive biomarkers of EE^sub 2^ effects on this species. The condition factor, hepatosomatic index, gonadal aromatase expression, sperm count and sperm velocities were unaltered after EE^sub 2^ exposure. The present work highlights the importance of using a combination of several biomarkers to study the effects of estrogenic compounds, especially when trying to link these results to potential population-level effects.[PUBLICATION ABSTRACT]
ISSN:0007-4861
1432-0800
DOI:10.1007/s00128-013-1185-2