Evaluation of DNA encoding acidic ribosomal protein P2 ofCryptosporidium parvumas a potential vaccine candidate for cryptosporidiosis

Highlights * P2 (CpP2) is an important immunodominant marker inC. parvuminfection. * Mice immunized with a DNA vaccine encoding theC. parvumP2 antigen were able to elicithumoral and cellular responses. * P2 antigen has potential to generate protective immunity againstC. parvuminfection.

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Bibliographic Details
Published in:Vaccine 2011-11, Vol.29 (49), p.9239
Main Authors: Benitez, Alvaro, Priest, Jeffrey W, Ehigiator, Humphrey N, McNair, Nina, Mead, Jan R
Format: Article
Language:English
Subjects:
Cryptosporidiosis
Cytokines
Deoxyribonucleic acid
Developing countries
DNA
Immune system
Immunization
Infections
LDCs
Parasitic diseases
Proteins
Vaccines
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Description
Summary:Highlights * P2 (CpP2) is an important immunodominant marker inC. parvuminfection. * Mice immunized with a DNA vaccine encoding theC. parvumP2 antigen were able to elicithumoral and cellular responses. * P2 antigen has potential to generate protective immunity againstC. parvuminfection.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.09.094