Polymeric Materials for Theranostic Applications

ABSTRACT Nanotechnology has continuously contributed to the fast development of diagnostic and therapeutic agents. Theranostic nanomedicine has encompassed the ongoing efforts on concurrent molecular imaging of biomarkers, delivery of therapeutic agents, and monitoring of therapy response. Among the...

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Bibliographic Details
Published in:Pharmaceutical research 2014-06, Vol.31 (6), p.1358-1376
Main Authors: Wang, Zhe, Niu, Gang, Chen, Xiaoyuan
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Biomedical and Life Sciences
Biomedical Engineering and Bioengineering
Biomedicine
Drug delivery systems
Expert Review
Humans
Medical imaging
Medical Law
Micelles
Nanomedicine - trends
Nanoparticles - therapeutic use
Nanotechnology
Nanotechnology - trends
Pharmacology/Toxicology
Pharmacy
Polymers
Polymers - therapeutic use
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Summary:ABSTRACT Nanotechnology has continuously contributed to the fast development of diagnostic and therapeutic agents. Theranostic nanomedicine has encompassed the ongoing efforts on concurrent molecular imaging of biomarkers, delivery of therapeutic agents, and monitoring of therapy response. Among these formulations, polymer-based theranostic agents hold great promise for the construction of multifunctional agents for translational medicine. In this article, we reviewed the state-of-the-art polymeric nanoparticles, from preparation to application, as potential theranostic agents for diagnosis and therapy. We summarized several major polymer formulas, including polymeric conjugate complexes, nanospheres, micelles, and dendrimers for integrated molecular imaging and therapeutic applications.
ISSN:0724-8741
1573-904X
DOI:10.1007/s11095-013-1103-7