Quantum Chemical and Experimental Studies on the Mechanism of Alkylation of [beta]-Dicarbonyl Compounds. The Synthesis of Five and Six Membered Heterocyclic Spiro Derivatives

The alkylation of β-dicarbonyl compounds in a K2CO3/DMSO system wasfound to afford O- and C-alkylated derivatives, depending on the type of the β-dicarbonylcompound involved. The alkyl derivatives obtained were used in the synthesis of some newspiro barbituric acid derivatives. Quantum chemical calc...

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Published in:Molecules (Basel, Switzerland) Switzerland), 2004-11, Vol.9 (11), p.922
Main Authors: Sadikov, Nurettin, Nasibov, Sahin, Ogretir, Cemil, Berber, Halil, Hüseyinli, Ali
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container_title Molecules (Basel, Switzerland)
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creator Sadikov, Nurettin
Nasibov, Sahin
Ogretir, Cemil
Berber, Halil
Hüseyinli, Ali
description The alkylation of β-dicarbonyl compounds in a K2CO3/DMSO system wasfound to afford O- and C-alkylated derivatives, depending on the type of the β-dicarbonylcompound involved. The alkyl derivatives obtained were used in the synthesis of some newspiro barbituric acid derivatives. Quantum chemical calculations were carried out toelucidate the reaction mechanisms for some typical synthesis.
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title Quantum Chemical and Experimental Studies on the Mechanism of Alkylation of [beta]-Dicarbonyl Compounds. The Synthesis of Five and Six Membered Heterocyclic Spiro Derivatives
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