Force-controlled manipulation of single cells: from AFM to FluidFM

Highlights • FluidFM combines AFM with microfluidics and represents a force-controlled nanopipette. • FluidFM allows multiple means to perturb, isolate, and analyze single cells. • Operation modes can be combined to perform sequential manipulations on a single cell.

Saved in:
Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2014-07, Vol.32 (7), p.381-388
Main Authors: Guillaume-Gentil, Orane, Potthoff, Eva, Ossola, Dario, Franz, Clemens M, Zambelli, Tomaso, Vorholt, Julia A
Format: Article
Language:English
Subjects:
atomic force microscopy
Biological and medical sciences
Biology
Biotechnology
Cell adhesion & migration
Experiments
fluidic force microscopy
Fundamental and applied biological sciences. Psychology
Humans
Internal Medicine
Microfluidics - instrumentation
Microfluidics - methods
Microscopes
Microscopy
Microscopy, Atomic Force - methods
Nanostructures - chemistry
Nanostructures - ultrastructure
Particle Size
single-cell analysis
Single-Cell Analysis - methods
single-cell perturbation
Spectrum analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • FluidFM combines AFM with microfluidics and represents a force-controlled nanopipette. • FluidFM allows multiple means to perturb, isolate, and analyze single cells. • Operation modes can be combined to perform sequential manipulations on a single cell.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2014.04.008