A study of hypoglycemic effects of Azadirachta indica (Neem) in human blood cells

The present investigation was conducted with an objective to validate the effect of the plant Azadirachta indica (neem) in human blood cells in a normoglycemic medium. This hypoglycemic effect had been attributed by the communities to this plant. In this study, aqueous extract of the plant was used...

Full description

Saved in:
Bibliographic Details
Published in:Emirates journal of food and agriculture 2014-07, Vol.26 (7), p.623
Main Authors: Martínez, Nubilde, Rodríguez, Yamileth, Salguero, Omar, Requena, Dayana, Triana, Ledia, Pérez-Ybarra, Luis
Format: Article
Language:English
Subjects:
Aqueous solutions
Colleges & universities
Glucose
Insulin
Leukocytes
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present investigation was conducted with an objective to validate the effect of the plant Azadirachta indica (neem) in human blood cells in a normoglycemic medium. This hypoglycemic effect had been attributed by the communities to this plant. In this study, aqueous extract of the plant was used in a concentration of 6.4% m/v and from this, following doses were prepared: 0.01 mg; 0.05 mg (low doses); 0.1 mg; 0.175 mg (medium doses); 0.7 mg and 1.4 mg (high doses); also it was used insulin Humulin R® in different concentrations (0.1, 1, 10 nM) in order to compare both effects in a normoglycemic medium with human blood cells. The results demonstrated a hypoglycemic effect when the levels of glucose concentration went down in the normoglycemic medium in relation to the control. There was a significant effect (p
ISSN:2079-052X
2079-0538
DOI:10.9755/ejfa.v26i7.18193