ORIGINAL ARTICLE: Should short children born small for gestational age with a distance to target height <1 standard deviation score be excluded from growth hormone treatment?

Summary Context  The criteria for starting growth hormone (GH), an approved treatment for short children born small for gestational age (SGA), differ between Europe and the USA. One European requirement for starting GH, a distance to target height (DTH) of ≥1 standard deviation score (SDS), is contr...

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Bibliographic Details
Published in:Clinical endocrinology (Oxford) 2010-09, Vol.73 (3), p.355-360
Main Authors: Lem, Annemieke J., De Kort, Sandra W. K., De Ridder, Maria A. J., Hokken-Koelega, Anita C. S.
Format: Article
Language:English
Subjects:
Growth hormones
Pediatrics
Physical growth
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Summary:Summary Context  The criteria for starting growth hormone (GH), an approved treatment for short children born small for gestational age (SGA), differ between Europe and the USA. One European requirement for starting GH, a distance to target height (DTH) of ≥1 standard deviation score (SDS), is controversial. Objective  To investigate the influence of DTH on growth during GH treatment in short SGA children and to ascertain whether it is correct to exclude children with a DTH
ISSN:0300-0664
1365-2265
DOI:10.1111/j.1365-2265.2010.03833.x