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Frequency and Practice-Level Variation in Inappropriate and Nonrecommended Prasugrel Prescribing

The current American College of Cardiology Foundation/American Heart Association guidelines for patients with ST-segment elevation myocardial infarction and unstable angina/non-ST-segment elevation myocardial infarction (3,4) assign a Class I recommendation for prasugrel use at the time of percutane...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2014-07, Vol.63 (25), p.2876-2877
Main Authors: Hira, Ravi S., MD, Kennedy, Kevin, MS, Jneid, Hani, MD, Alam, Mahboob, MD, Basra, Sukhdeep S., MD, MPH, Petersen, Laura A., MD, MPH, Ballantyne, Christie M., MD, Nambi, Vijay, MD, PhD, Chan, Paul S., MD, MSc, Virani, Salim S., MD, PhD
Format: Article
Language:English
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Summary:The current American College of Cardiology Foundation/American Heart Association guidelines for patients with ST-segment elevation myocardial infarction and unstable angina/non-ST-segment elevation myocardial infarction (3,4) assign a Class I recommendation for prasugrel use at the time of percutaneous coronary intervention (PCI) and a Class III (harm) recommendation for its use in patients with history of TIA or stroke. Patients in the appropriate indication group had higher rates of private insurance and treatment by a physician provider; patients in the inappropriate indication group had a higher prevalence of comorbidities such as diabetes, hypertension, dyslipidemia, atrial fibrillation, heart failure, peripheral artery disease, and coronary arterial bypass graft surgery.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2014.04.011