IMPACT OF HIGH-FAT, LOW-CARBOHYDRATE DIET ON INSULIN SENSITIVITY AND TCA CYCLE SUBSTRATE ENTRY DURING ISCHEMIA-REPERFUSION

Isolated hearts were subjected to 30 min low flow ischemia (0.3 ml/min) followed by 60 min reperfusion, using a physiologic substrate mixture and carbon-13 labeled substrates, and TCA cycle entry determined by C-13 NMR spectroscopy.

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Published in:Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E438-E438
Main Authors: Lloyd, Steven G, Wang, Peipei, Tate, Joshua M, Douglas, Samuel L
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular
Diet
Insulin
Internal Medicine
Ischemia
Phosphorylation
Rodents
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container_end_page E438
container_issue 13
container_start_page E438
container_title Journal of the American College of Cardiology
container_volume 59
creator Lloyd, Steven G
Wang, Peipei
Tate, Joshua M
Douglas, Samuel L
description Isolated hearts were subjected to 30 min low flow ischemia (0.3 ml/min) followed by 60 min reperfusion, using a physiologic substrate mixture and carbon-13 labeled substrates, and TCA cycle entry determined by C-13 NMR spectroscopy.
doi_str_mv 10.1016/S0735-1097(12)60439-2
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subjects Cardiology
Cardiovascular
Diet
Insulin
Internal Medicine
Ischemia
Phosphorylation
Rodents
title IMPACT OF HIGH-FAT, LOW-CARBOHYDRATE DIET ON INSULIN SENSITIVITY AND TCA CYCLE SUBSTRATE ENTRY DURING ISCHEMIA-REPERFUSION
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