CSL112, A NOVEL FORMULATION OF HUMAN APOA-I, RAPIDLY ENHANCES CHOLESTEROL EFFLUX CAPACITY OF PLASMA FOLLOWING INFUSION

The efflux of cellular cholesterol mediated by apoA-I and ATP-binding cassette transporter A1 (ABCA1) is thought to underlie many of the cardiovascular benefits of HDL.

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E491-E491
Main Authors: Easton, Rachael, Diditchenko, Svetlana, Spycher, Martin, Waelchli, Marcel, Imboden, Martin, Schenk, Sabrina, Pragst, Ingo, Wright, Samuel D, AG, CSL Behring
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular
Cholesterol
Internal Medicine
Plasma
Online Access:Get full text
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Description
Summary:The efflux of cellular cholesterol mediated by apoA-I and ATP-binding cassette transporter A1 (ABCA1) is thought to underlie many of the cardiovascular benefits of HDL.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(12)60492-6