Detecting Galactomannan in an Aspergillus Outbreak Investigation within a Bone Marrow Transplant Unit: A Puzzle with a Missing Piece

In September 2012, Los Angeles County (LAC) Department of Public Health (DPH) was notified of nine patients hospitalized on the bone marrow transplant unit (BMT) with blood specimens positive for galactomannan (GM) antigen between September 3, 2012 and September 11, 2012. The Bio-Rad Platelia(TM) As...

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Bibliographic Details
Published in:American journal of infection control 2014-06, Vol.42 (6), p.S151-S152
Main Authors: Silvaggio, Jessica, MPH, English, L'Tanya, RN, Marquez, Patricia, MPH, Terashita, Dawn, MD, MPH, Mascola, Laurene, MD, MPH, Masis, Evenor, MS, REHS, Vasquez, Robert, REHS
Format: Article
Language:English
Subjects:
Bone marrow
Hospitals
Infection Control
Infectious Disease
Nosocomial infections
Transplants & implants
Online Access:Get full text
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Summary:In September 2012, Los Angeles County (LAC) Department of Public Health (DPH) was notified of nine patients hospitalized on the bone marrow transplant unit (BMT) with blood specimens positive for galactomannan (GM) antigen between September 3, 2012 and September 11, 2012. The Bio-Rad Platelia(TM) Aspergillus Ag assay is noninvasive and was used to test all case specimens for GM. There are many documented cases of false positives with this test. An outbreak investigation was begun.
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2014.03.323