EFECTO DEL FLUORURO DIAMINO DE PLATA EN CARIES INDUCIDA EN RATAS WISTAR/THE EFFECT OF SILVER DIAMINE FLUORIDE ON CARIES INDUCED IN WISTAR RATS

• Published in: Revista de la Facultad de Odontología Universidad de Antioquia 2014-07, Vol.26 (1), p.76
• Main Authors: Vanegas, Susana, Godoy, Astrid, Urdaneta, Leonidas, Olávez, Daniela, Padrón, Karla, Solórzano, Eduvigis
• Format: Article
• Language: eng ; spa
• ISSN: 0121-246X; 2145-7670

Dental caries is considered a public health problem. Various biomaterials have been suggested for treating it, including fluride+silver nitrate mix, known as silver diamine fluoride (SDF) which contains cariostatic, remineralizing, and bactericide properties and is used on primary teeth. Only a few studies have assessed the response of dental tissue when this substance is applied; the objective of this study was therefore to determine the effect of SDF on caries induced in Wistar rats. Dental caries was induced in Wistar rats' molars by inoculating them with S. mutans CVCM656 and feeding them a sucrose-rich diet for 12 weeks. Once caries were diagnosed and sorted out into control groups and experimental groups, softened dentine was removed from molars; only the molars from experimental groups received a topical application of 3.8% SDF. The control groups experienced an increased number of carious lesions and progression in severity, while the same parameters in the experimental groups remained unchanged, showing hard dark dentine surfaces.