Antiretroviral therapy attenuates dysregulated hematopoiesis caused by chronic binge alcohol and SIV infection in rhesus macaques

Following the 10 weeks ART administration period, we observed decreased frequencies of long-term hematopoietic stem cells and multipotent progenitor cells in CBA, ART naïve animals, and this deficit was not observed in ART-treated animals.

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Bibliographic Details
Published in:Alcohol (Fayetteville, N.Y.) N.Y.), 2014-11, Vol.48 (7), p.730-730
Main Authors: Li, L.W, Bagby, G.J, Nelson, S, Molina, P.E, Welsh, D.A, Siggins, R.W
Format: Article
Language:English
Subjects:
Alcohol
Animals
Bone marrow
HIV
Human immunodeficiency virus
Infections
Psychiatry
Stem cells
Sucrose
Online Access:Get full text
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Description
Summary:Following the 10 weeks ART administration period, we observed decreased frequencies of long-term hematopoietic stem cells and multipotent progenitor cells in CBA, ART naïve animals, and this deficit was not observed in ART-treated animals.
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2014.09.014