Potentiality of a live vaccine with nervous necrosis virus (NNV) for sevenband grouperEpinephelus septemfasciatusat a low rearing temperature

Highlights * Mortality of fish due to NNV were reduced by decreasing fish rearing temperature. * No mortality was observed in the fish reared at 17°C. * The survivors mounted a specific protective immune response against NNV. * NNV titer was far below the NNV critical level but above the threshold l...

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Bibliographic Details
Published in:Vaccine 2012-02, Vol.30 (6), p.1056
Main Authors: Nishizawa, Toyohiko, Gye, Hyun Jung, Takami, Ikuo, Oh, Myung-Joo
Format: Article
Language:English
Subjects:
Fish
Fish diseases
Flounder
Immune response
Infections
Mortality
Temperature
Vaccines
Viruses
Online Access:Get full text
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Summary:Highlights * Mortality of fish due to NNV were reduced by decreasing fish rearing temperature. * No mortality was observed in the fish reared at 17°C. * The survivors mounted a specific protective immune response against NNV. * NNV titer was far below the NNV critical level but above the threshold level. * Suggesting the potentiality of a live NNV vaccine by rearing fish at 17°C.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.12.033