Protection of pigs against genitalChlamydia trachomatischallenge by parenteral or mucosal DNA immunization

Highlights * Evaluation of a MOMP-basedChlamydia trachomatisDNA vaccine in a pig model. * Comparing mucosal and parenteral administration of the vaccine. * Significant protection against aC. trachomatisinfection was induced by mucosal vaccination. * Parenteral immunization did not lead to significan...

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Bibliographic Details
Published in:Vaccine 2012-04, Vol.30 (18), p.2869
Main Authors: Schautteet, Katelijn, De Clercq, Evelien, Jönsson, Yannick, Lagae, Stefanie, Chiers, Koen, Cox, Eric, van rompay, Daisy
Format: Article
Language:English
Subjects:
Animals
Antigens
Deoxyribonucleic acid
DNA
E coli
Females
Hogs
Immunization
Infections
Lymphocytes
Plasmids
Sexually transmitted diseases
STD
Vaccines
Women
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Summary:Highlights * Evaluation of a MOMP-basedChlamydia trachomatisDNA vaccine in a pig model. * Comparing mucosal and parenteral administration of the vaccine. * Significant protection against aC. trachomatisinfection was induced by mucosal vaccination. * Parenteral immunization did not lead to significant protection.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.02.044