GW25-e1586 Panaxquin quefolium diolsaponins dose-dependently inhibits the proliferation of vascular smooth muscle cells by downregulating proto-oncogene expression

AngII promoted cell proliferation, whereas PQDS significantly suppressed VSMC growth in a dose-dependent manner. [...]PQDS suppressed AngII-induced proliferation of VSMCs by arresting the Gap 0/Gap 1 phase.

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Published in:Journal of the American College of Cardiology 2014-10, Vol.64 (16), p.C86-C86
Main Authors: Zhihao, Wang, Yingkai, Wang, Xuezhong, Zhao
Format: Article
Language:English
Subjects:
Atherosclerosis
Cardiology
Cardiovascular
Cardiovascular disease
Cell growth
Internal Medicine
Rodents
Smooth muscle
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container_end_page C86
container_issue 16
container_start_page C86
container_title Journal of the American College of Cardiology
container_volume 64
creator Zhihao, Wang
Yingkai, Wang
Xuezhong, Zhao
description AngII promoted cell proliferation, whereas PQDS significantly suppressed VSMC growth in a dose-dependent manner. [...]PQDS suppressed AngII-induced proliferation of VSMCs by arresting the Gap 0/Gap 1 phase.
doi_str_mv 10.1016/j.jacc.2014.06.399
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subjects Atherosclerosis
Cardiology
Cardiovascular
Cardiovascular disease
Cell growth
Internal Medicine
Rodents
Smooth muscle
title GW25-e1586 Panaxquin quefolium diolsaponins dose-dependently inhibits the proliferation of vascular smooth muscle cells by downregulating proto-oncogene expression
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