GW25-e4163 Effects of Astragaloside on Cardiac Function of rats with Cecal Ligation and Puncture and Underlying Mechanism

Conclusions AST could effectively extend the survival time, significantly assuage the cardiac function and decrease myocardial necrosis and apoptosis in septic rats indused by CLP, which may be relative with the expression of iNOS and AMPK.

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2014-10, Vol.64 (16), p.C69-C69
Main Authors: Xin, Huang, Ma, Shi-yu, Yin, Xin, Liu, Qin, Chen, Yan-fen, Zhang, Min-zhou, Guo, Li-heng
Format: Article
Language:English
Subjects:
Apoptosis
Cardiology
Cardiovascular
Internal Medicine
Proteins
Rodents
Online Access:Get full text
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Description
Summary:Conclusions AST could effectively extend the survival time, significantly assuage the cardiac function and decrease myocardial necrosis and apoptosis in septic rats indused by CLP, which may be relative with the expression of iNOS and AMPK.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2014.06.327