The relationship between gamma-glutamyltransferase and coronary collateral circulation in patients with chronic total occlusion

• Published in: Anadolu kardiyoloji dergisi : AKD 2014-02, Vol.14 (1), p.48-54
• Main Authors: Şahin, Müslüm, Demir, Serdar, Kalkan, Mehmet Emin, Özkan, Birol, Alıcı, Gökhan, Çakalağaoğlu, Kamil Cantürk, Yazıcıoğlu, Mehmet Vefik, Sarıkaya, Sabit, Biteker, Murat, Türkmen, Mehmet Muhsin
• Format: Article
• Language: English
• Subjects: Acute Coronary Syndrome - blood; Biomarkers - blood; Collateral Circulation; Cross-Sectional Studies; gamma-Glutamyltransferase - blood; Humans; ROC Curve; Severity of Illness Index
• ISSN: 1302-8723; 2149-2263; 1308-0032; 2149-2271
• DOI: 10.5152/akd.2013.236

The aim of this study was to evaluate the relation between blood gamma-glutamyltransferase (GGT) levels and coronary collateral circulation in patients with chronic total occlusion (CTO). Two hundred twenty-two patients with chronic stable coronary artery disease (CAD) and CTO were included in this cross-sectional, observational study. Coronary collaterals were graded from 0 to 3 according to the Rentrop method. Patients with grade 0-1 collateral development were regarded as poor collateral group (n=66) while patients with grade 2-3 collateral development were regarded as good collateral group (n=156). Statistical analysis was performed using independent samples t, Mann-Whitney U and Chi-square tests, logistic regression and receiver operator curve analysis. The poor coronary collateral group had significantly higher levels of serum GGT compared to the good collateral group (p