Absence status after starting clobazam in a patient with syndrome of continuous spike and wave during slow sleep (CSWS)

Sir, Continuous spike and wave during slow sleep (CSWS) is a rare but devastating pediatric epileptic encephalopathy characterized by global neuropsychiatric regression and electroencephalogram (EEG) activation during non-rapid eye movement (NREM) sleep. [4] Paradoxical aggravation of idiopathic gen...

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Bibliographic Details
Published in:Neurology India 2014-11, Vol.62 (6), p.685
Main Authors: Samanta, Debopam, Willis, Erin, Sharp, Gregory B
Format: Article
Language:English
Subjects:
Anticonvulsants - administration & dosage
Anticonvulsants - adverse effects
Benzodiazepines - administration & dosage
Benzodiazepines - adverse effects
Case studies
Child
Clobazam
Developmental Disabilities - drug therapy
Diagnosis
Drug therapy
Electroencephalography
Encephalopathy
Epilepsy
Epilepsy, Absence - chemically induced
Epilepsy, Absence - diagnosis
Health aspects
Humans
Male
Medical research
Pediatrics
Sleep
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Summary:Sir, Continuous spike and wave during slow sleep (CSWS) is a rare but devastating pediatric epileptic encephalopathy characterized by global neuropsychiatric regression and electroencephalogram (EEG) activation during non-rapid eye movement (NREM) sleep. [4] Paradoxical aggravation of idiopathic generalized epilepsy has been reported with different AEDs including carbamazepine and phenytoin, but no report of clobazam-induced absence status has been reported in the literature to the best of our knowledge.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.149410