PP-044 Intracoronary Administration of Tirofiban and Alteplase during Percutenous Coronary Intervention to a Saphenous Vein Graft with Extensive Thrombi

In the event of angiographic evidence of large thrombus as seen in stent thrombosis, slow- or no-reflow phenomenon and other thrombotic complications, use of GP IIb/IIIa inhibitors as bail-out therapy seems reasonable. Tirofiban was administered as an intracoronary bolus injection (10[micro]g/kg ove...

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Bibliographic Details
Published in:The American journal of cardiology 2015-03, Vol.115, p.S117-S117
Main Authors: Okyay, Kaan, Yıldırır, Aylin, Bal, Uğur, Muderrisoğlu, Haldun
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Cardiology
Cardiovascular
Heart attacks
Intervention
Medical imaging
Veins & arteries
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Summary:In the event of angiographic evidence of large thrombus as seen in stent thrombosis, slow- or no-reflow phenomenon and other thrombotic complications, use of GP IIb/IIIa inhibitors as bail-out therapy seems reasonable. Tirofiban was administered as an intracoronary bolus injection (10[micro]g/kg over 3 min) followed by maintenance intravenous infusion at 0.15[micro]g*kg-1*min-1 for 24 h. Additonally, a 10 mg of Alteplase (t-PA) diluted with 20 ml of saline and given through the guiding catheter within 3 minutes.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2015.01.400