VPLIV TRAMADOLA NA ZDRAVLJENJE POOPERATIVNE BOLEcINE PO ODSTRANITVI ZRELNICE IN NEBNIC PRI OTROCIH

• Published in: Zdravniški vestnik (Ljubljana, Slovenia : 1992) Slovenia : 1992), 2015-04, Vol.84 (4)
• Main Author: Benedik, Janez
• Format: Article
• Language: Slovenian
• Subjects: Analgesics; Comparative studies; Narcotics; Pain management; Throat surgery
• ISSN: 1318-0347; 1581-0024

Background: Tonsillectomy is one of the most commonly performed surgical prcedures in childhood. Acute pain aer tonsillectomy and adenoidectomy can be treated with non-opioid and opioid analgesics. Our hypothesis stated that tramadol iv aer induction of anaesthesia has a superior analgesic eect compared to acetaminophen. Methods: In a prospective, randomised study we compared analgesic efficacy of tramadol (group T: 2 mg/kgBW iv) and acetaminophen (group A: elixir 15 mg/kgBW before op. procedure) in a group of 108 children (age 37 years). Exclusion critheria: allergy, liver or kidney failure, epilepsy, febrile convulsions. A standard anaesthetic technique was used: propofol, alfentanil, vecuronium, positive pressure ventilation with 60 % nitrous oxide in oxygen. Aer the procedure, each child received acetaminophen suppositories (10 mg/ kgBW/46h; VAS 35) and combined supposi-tories (1 supp./15kgBW/68h; VAS > 5). Monitoring: vital signs during and aer op. procedure, pain intensity on the ward (facial pain score). Results: There were no signicant dierences in age distribution (mean age 5.2 years), ASA physical status, body weight, operative procedure, pain scores (VAS 6h aer operative procedure; group T: 4.21 1.45; group A: 4.06 1.33), oxygen saturation, pulse frequency and the consumption of acetaminophen suppositories between the two groups. There was a signicant dierence in the consumption of combined suppositories (group T: 1.85 0.79; group A: 1.43 0.69, p = 0.003). Conclusion: Our study has shown, that tramadol is not a superior analgesic for the relief of posttonsillectomy pain in children compared to acetaminophen.