Epigenetic changes mediated by the polycomb repressor complex 1 in acinar-to-ductal metaplasia and pancreatic carcinogenesis

Expression of PRC1 members was analyzed in 3D-cultured pancreatic acinar explants and in cerulein-treated oncogenic KrasG12D and wildtype mice with immunohistochemistry, Western Blot and qRT-PCR analysis.

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Bibliographic Details
Published in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2015-06, Vol.15 (3), p.S44-S44
Main Authors: Benitz, Simone, Regel, Ivonne, Reinhard, Tobias, Guo, Jessica, Popp, Anna, Schäffer, Isabell, Kong, Bo, Raulefs, Susanne, Kleeff, Jörg, Michalski, Christoph W
Format: Article
Language:English
Subjects:
Chromatin
Endocrinology & Metabolism
Epigenetics
Gastroenterology and Hepatology
Gene expression
Pancreatic cancer
Rodents
Online Access:Get full text
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Description
Summary:Expression of PRC1 members was analyzed in 3D-cultured pancreatic acinar explants and in cerulein-treated oncogenic KrasG12D and wildtype mice with immunohistochemistry, Western Blot and qRT-PCR analysis.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2015.05.180