Influence of Formulation Change and Cyp2c19 Genotypes On Pharmacokinetics of Single-Dose Rabeprazole In Healthy Chinese Adults By Lc-Ms/Ms

Results In injection group, plasma half-time (t1/2) was 1.20 ± 0.5h, the area under plasma concentration-time curve (AUC) was 1410.34 ± 395.69 [micro]g/h/L, and clearance (CL) was 15.25 ± 4.25 L/h.

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Bibliographic Details
Published in:Clinical therapeutics 2015-08, Vol.37 (8), p.e72-e72
Main Authors: Wang, Z, Du, Y.Q, Wan, S.H, Zhao, N.P, Zhou, J, Tang, S.X, Kang, X, Cai, T.T, Yang, W.Y, Zhang, L, Gao, S, Li, Z.S
Format: Article
Language:English
Subjects:
Bioavailability
Internal Medicine
Medical Education
Online Access:Get full text
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Description
Summary:Results In injection group, plasma half-time (t1/2) was 1.20 ± 0.5h, the area under plasma concentration-time curve (AUC) was 1410.34 ± 395.69 [micro]g/h/L, and clearance (CL) was 15.25 ± 4.25 L/h.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.492