A Case report of suicide in a teenager with long-term use of fluoxetine associated with CYP2D6 Polymorphism

Conclusions Fluoxetine use may cause toxic drug accumulation thus leading to worsening of suicidal thoughts if taken by teenagers with possible genetic determined insufficiency of CYP2D6 enzyme (poor metabolizer).

Saved in:
Bibliographic Details
Published in:Clinical therapeutics 2015-08, Vol.37 (8), p.e95-e95
Main Authors: Asriyants, S.V, Veselkina, O.V, Sychev, D.A, Obuhova, Y.D, Polyakov, A.V, Klevno, V.A
Format: Article
Language:English
Subjects:
Antidepressants
Enzymes
Internal Medicine
Medical Education
Suicides & suicide attempts
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Conclusions Fluoxetine use may cause toxic drug accumulation thus leading to worsening of suicidal thoughts if taken by teenagers with possible genetic determined insufficiency of CYP2D6 enzyme (poor metabolizer).
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.272