Randomized Clinical Trial, Placebo Compared To Evaluate The Efficacy And Safety of Minocycline In Angelman Syndrome (A-Manece Study)

Angelman syndrome (AS) is a rare disease with serious developmental disorder. [...]no cure for AS exists. Recently published studies show an improvement of motor function, cognition and increased synaptic function in animal models with minocycline administration.

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Bibliographic Details
Published in:Clinical therapeutics 2015-08, Vol.37 (8), p.e154-e155
Main Authors: Ruiz-Antorán, B, Sancho López, A, Cazorla, R, Iglesias, G, Lara, J, López Pájaro, L, Marín, E, Avendaño-Solá, C
Format: Article
Language:English
Subjects:
Clinical trials
Internal Medicine
Medical Education
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Description
Summary:Angelman syndrome (AS) is a rare disease with serious developmental disorder. [...]no cure for AS exists. Recently published studies show an improvement of motor function, cognition and increased synaptic function in animal models with minocycline administration.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.442