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Robust Control for cultivation of microorganisms in a high density fed-batch bioreactor

In this paper a nonlinear algorithm for adaptive control of a fed-batch bioreactor for high density cultures is proposed. The control of these processes is difficult due to parameter variations and process disturbances. The control scheme is based on a reduced model used to estimate the uncertaintie...

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Bibliographic Details
Published in:Revista IEEE América Latina 2015-06, Vol.13 (6), p.1927-1933
Main Authors: Rodriguez, Abraham E., Torres Munoz, Jorge Antonio, Luna, Ricardo, Perez Correa, Jose Ricardo, Dominguez Bocanegra, A.R., Sira Ramirez, Hebert, Castro, R
Format: Article
Language:English
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Summary:In this paper a nonlinear algorithm for adaptive control of a fed-batch bioreactor for high density cultures is proposed. The control of these processes is difficult due to parameter variations and process disturbances. The control scheme is based on a reduced model used to estimate the uncertainties with adaptive techniques. Convergence of estimated biomass to a desired neighborhood was proved based on the reduced model. The good performance of the control scheme was verified with full model simulations of the bioreactor simulations.
ISSN:1548-0992
1548-0992
DOI:10.1109/TLA.2015.7164219