Robust Control for cultivation of microorganisms in a high density fed-batch bioreactor

In this paper a nonlinear algorithm for adaptive control of a fed-batch bioreactor for high density cultures is proposed. The control of these processes is difficult due to parameter variations and process disturbances. The control scheme is based on a reduced model used to estimate the uncertaintie...

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Published in:Revista IEEE América Latina 2015-06, Vol.13 (6), p.1927-1933
Main Authors: Rodriguez, Abraham E., Torres Munoz, Jorge Antonio, Luna, Ricardo, Perez Correa, Jose Ricardo, Dominguez Bocanegra, A.R., Sira Ramirez, Hebert, Castro, R
Format: Article
Language:English
Subjects:
Adaptation models
Adaptive control
Biological system modeling
nonlinear control
Overflow metabolism
Process control
Robust control
Robustness
Silicon compounds
yeast
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container_end_page 1933
container_issue 6
container_start_page 1927
container_title Revista IEEE América Latina
container_volume 13
creator Rodriguez, Abraham E.
Torres Munoz, Jorge Antonio
Luna, Ricardo
Perez Correa, Jose Ricardo
Dominguez Bocanegra, A.R.
Sira Ramirez, Hebert
Castro, R
description In this paper a nonlinear algorithm for adaptive control of a fed-batch bioreactor for high density cultures is proposed. The control of these processes is difficult due to parameter variations and process disturbances. The control scheme is based on a reduced model used to estimate the uncertainties with adaptive techniques. Convergence of estimated biomass to a desired neighborhood was proved based on the reduced model. The good performance of the control scheme was verified with full model simulations of the bioreactor simulations.
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subjects Adaptation models
Adaptive control
Biological system modeling
nonlinear control
Overflow metabolism
Process control
Robust control
Robustness
Silicon compounds
yeast
title Robust Control for cultivation of microorganisms in a high density fed-batch bioreactor
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