Consumption of Argan Oil Improves Anti-Oxidant and Lipid Status in Hemodialysis Patients

Objective: Virgin Argan oil (VAO) is of interest in oxidative stress and lipid profile because of its fat composition and antioxidant compounds. We investigated the effect of VAO consumption on lipid profile and antioxidant status in hemodialysis patients after a 4‐week period of consumption. Method...

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Bibliographic Details
Published in:Phytotherapy research 2015-10, Vol.29 (10), p.1595-1599
Main Authors: Eljaoudi, Rachid, Elkabbaj, Driss, Bahadi, Abdelali, Ibrahimi, Azeddine, Benyahia, Mohammed, Errasfa, Mourad
Format: Article
Language:English
Subjects:
Adult
Aged
Antioxidants - administration & dosage
Argan oil
Cholesterol - blood
chronic renal failure
Diet
Female
Humans
lipid profile
Lipids - blood
Lipoproteins, HDL - blood
Lipoproteins, LDL
Male
Malondialdehyde - blood
Middle Aged
Oxidants
oxidative stress
Oxidative Stress - drug effects
Plant Oils - administration & dosage
Renal Dialysis
Sapotaceae
Triglycerides - blood
Vitamin E - pharmacology
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Summary:Objective: Virgin Argan oil (VAO) is of interest in oxidative stress and lipid profile because of its fat composition and antioxidant compounds. We investigated the effect of VAO consumption on lipid profile and antioxidant status in hemodialysis patients after a 4‐week period of consumption. Methods: In a crossover, controlled trial, 37 patients (18 men, 19 women) with end‐stage renal disease on maintenance hemodialysis, were randomly assigned to a 4‐week VAO diet. Fasting plasma lipids, vitamin E and oxidized LDL (ox‐LDL) were analyzed. Malondialdehyde (MDA) was determined before and after hemodialysis session. Results: There was no significant change in serum total cholesterol and ox‐LDL. However, VAO consumption decreased the levels of triglyceride (p = 0.03), total cholesterol (p = 0.02) and low‐density lipoprotein (p = 0.03) and increased the levels of high‐density lipoprotein (p = 0.01). Plasma vitamin E contents significantly increased from baseline only in VAO‐group (p 
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.5405