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GW26-e2106 The Impact of the Drug Composition Containing Medicine Serum Contains Cassia Twig Liquorice Decoction Components on ICa- L of Guinea Pig Single Ventricular Myocyte
Methods Preparing the medicated serum of rats, acute isolated guinea pigs single ventricular myocyte, will receive the ventricular muscle cells suspension after returning to the physiologic calcium concentration, respectively with blank group containing the concentration of 15% (irrigation suits sal...
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Published in: | Journal of the American College of Cardiology 2015-10, Vol.66 (16), p.C23-C23 |
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container_title | Journal of the American College of Cardiology |
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creator | Wang, Yongxia Xing, Zuoying Zhu, Chulin Cao, Yingjie Yuan, Shuangxing Liu, Hongjun Wang, Youping Gao, Yuan Li, Bin Zhu, Mingjun |
description | Methods Preparing the medicated serum of rats, acute isolated guinea pigs single ventricular myocyte, will receive the ventricular muscle cells suspension after returning to the physiologic calcium concentration, respectively with blank group containing the concentration of 15% (irrigation suits saline), licorice group (liquorice decoction), cassia twig group (cassia twig decoction), liquorice and cassia twig group (liquorice decoction and cassia twig decoction mixed) and cassia twig liquorice decoction group (cassia twig and licorice by 2:1 ratio mixed decoction), in the medicated serum of rats in 37 °C, 5% CO2 incubation box incubating cells after 24 hours, switch to the corresponding myocardial cell inside and outside liquid, patch clamp technique was used to measure the peak current density, the activation and inactivation time constant, recovery time constant of the myocardial cells of ICa-L, change between groups were analyzed. |
doi_str_mv | 10.1016/j.jacc.2015.06.1116 |
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title | GW26-e2106 The Impact of the Drug Composition Containing Medicine Serum Contains Cassia Twig Liquorice Decoction Components on ICa- L of Guinea Pig Single Ventricular Myocyte |
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