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On the basis of the case of subject 5, however, one could hypothesize additional groups, such as one consisting of cephalosporins such as cefamandole, cefoperazone, and cefotetan that share an identical R2 side chain with an N-methyl-tetrazole-thiol group. [...]we agree with Baldo and Pham that one...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2015-11, Vol.136 (5), p.1428
Main Authors: Romano, Antonino, Gaeta, Francesco, Valluzzi, Rocco Luigi, Maggioletti, Michela, Zaffiro, Alessandra, Caruso, Cristiano, Quaratino, Donato
Format: Article
Language:English
Subjects:
Amino acids
Crystal structure
Online Access:Get full text
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Summary:On the basis of the case of subject 5, however, one could hypothesize additional groups, such as one consisting of cephalosporins such as cefamandole, cefoperazone, and cefotetan that share an identical R2 side chain with an N-methyl-tetrazole-thiol group. [...]we agree with Baldo and Pham that one should take into account the antigenic determinants of both R1 and R2 side chains before administering alternative cephalosporins to subjects allergic to these β-lactams.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.06.053