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On the basis of the case of subject 5, however, one could hypothesize additional groups, such as one consisting of cephalosporins such as cefamandole, cefoperazone, and cefotetan that share an identical R2 side chain with an N-methyl-tetrazole-thiol group. [...]we agree with Baldo and Pham that one...

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Published in:Journal of allergy and clinical immunology 2015-11, Vol.136 (5), p.1428
Main Authors: Romano, Antonino, Gaeta, Francesco, Valluzzi, Rocco Luigi, Maggioletti, Michela, Zaffiro, Alessandra, Caruso, Cristiano, Quaratino, Donato
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Language:English
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Amino acids
Crystal structure
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container_issue 5
container_start_page 1428
container_title Journal of allergy and clinical immunology
container_volume 136
creator Romano, Antonino
Gaeta, Francesco
Valluzzi, Rocco Luigi
Maggioletti, Michela
Zaffiro, Alessandra
Caruso, Cristiano
Quaratino, Donato
description On the basis of the case of subject 5, however, one could hypothesize additional groups, such as one consisting of cephalosporins such as cefamandole, cefoperazone, and cefotetan that share an identical R2 side chain with an N-methyl-tetrazole-thiol group. [...]we agree with Baldo and Pham that one should take into account the antigenic determinants of both R1 and R2 side chains before administering alternative cephalosporins to subjects allergic to these β-lactams.
doi_str_mv 10.1016/j.jaci.2015.06.053
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subjects Amino acids
Crystal structure
title Reply
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