Effect of prevention on the incidence of BRONJ: three years clinical follow-up

From Jan 1, 2009 to December 2011, all patients candidate to bisphosphonates (BP) therapy were referred to the Department of Dentistry and Oral Surgery of the University Hospital of Pisa in order to search and eliminate all oral osteonecrosis of the jaw (ONJ) risk factors and to correct dental condi...

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Bibliographic Details
Published in:Annali di stomatologia 2015-04, Vol.6 (1), p.66
Main Author: Nisi, M
Format: Article
Language:English
Subjects:
Cancer
Cancer therapies
Metastasis
Multiple myeloma
Risk factors
Studies
Online Access:Get full text
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Summary:From Jan 1, 2009 to December 2011, all patients candidate to bisphosphonates (BP) therapy were referred to the Department of Dentistry and Oral Surgery of the University Hospital of Pisa in order to search and eliminate all oral osteonecrosis of the jaw (ONJ) risk factors and to correct dental conditions that were thought to negatively influence oral health during BP therapy. At the first visit, all patients underwent a clinical oral examination and radiological assessment using orthopantomography. All potential ONJ risk factors were evaluated and corrected. At the end of this first preliminary examination, if patients were diagnosed as free to the previous conditions, they were considered eligible for future therapy. If this was not the case, patients were accordingly treated and planned for a second preliminary visit. A total of 892 subjects were identified and included in the present study. Only 60.1% of the sample was considered eligible to begin zoledronic therapy. At three years follow-up no bisphosphonate-related osteonecrosis of the jaw cases were detected.
ISSN:1824-0852
1971-1441