Prognostic role of C-reactive protein in acute stroke

• Published in: Bangladesh journal of medical science (Ibn Sina Trust) 2011-01, Vol.10 (1), p.29-33
• Main Authors: Rahman, MM, Rabim, MA, Nath, RK, Al-Mahmood, AK, Mollah, FH
• Format: Article
• Language: English
• ISSN: 2223-4721; 2076-0299
• DOI: 10.3329/bjms.v10i1.7316

Background & objective: Stroke is a dreadful health hazard all over the world as well as in our country and one of the leading causes of mortality & morbidity. The relationship between serum C-reactive protein (CRP) level and post stroke outcome is not well studied especially in Bangladesh. We were interested to study this relationship in our country. Materials & methods: A cross sectional prospective study was performed on 50-stroke patients. Serum CRP & Lipid profile was determined. Post stroke outcome was measured by modified ranking scale (good outcome, score within 0 – 2 & bad outcome, score within 3 – 6). The subjects were divided in two groups, CRP level above or below 10 mg/L. Statistical analysis was performed by using SPSS software. Chi-square test & Spearman’s rho correlation test was done to see the level of significance. Results: Mean serum CRP level was 9.69 mg/L that was higher than normal subjects. Correlation analysis between serums CRP level of stroke patients with post stroke outcome was found to be positively correlated (r = 0.598/p