Variation of in Vitro Glucocorticoid Response in Asthma

The association of steroid insensitivity and older age, obesity, and worse airflow limitation needs further investigation, as this may imply a need for increased doses of GC to overcome inflammation or airflow limitation in patients who are already susceptible to develop adverse effects.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB215-AB215
Main Authors: Reddy, Monica B., MD, Leung, Donald Y.M., MD, PhD, FAAAAI, Spahn, Joseph D., MD, Curran-Everett, Douglas, PhD, Knight, Vijaya, MD, PhD, Covar, Ronina A., MD, FAAAAI
Format: Article
Language:English
Subjects:
Allergy and Immunology
Asthma
Online Access:Get full text
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Description
Summary:The association of steroid insensitivity and older age, obesity, and worse airflow limitation needs further investigation, as this may imply a need for increased doses of GC to overcome inflammation or airflow limitation in patients who are already susceptible to develop adverse effects.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.1291