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Targeting Factor 12 (F12) with a Novel RNAi Delivery Platform As a Prophylactic Treatment for Hereditary Angioedema (HAE)

Structure activity relationship (SAR) studies of the most active RNAi triggers identified optimal modifications enabling lead identification.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB251-AB251
Main Authors: Melquist, Stacey, Wakefield, Darren, Hamilton, Holly, Chu, Qili, Almeida, Aaron, Almeida, Lauren, Walters, Megan, Montez, Jessica, Hegge, Julia, Klein, Jason, Hazlett, Christine, Milarch, Tracie, Bertin, Stephanie, Andersen, Aaron, Doss, Edie, Schmidt, Rachael, Goth, Linda, Ferger, Sheryl, Rozema, David, Hamilton, James, Lewis, David, Kanner, Steven
Format: Article
Language:English
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Description
Summary:Structure activity relationship (SAR) studies of the most active RNAi triggers identified optimal modifications enabling lead identification.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.905