PAI-1, Early Life Infections and Asthma Risk, Exacerbations, and Reduced Lung Function

Conclusions A genetic variant of PAI-1 together with early life LRI such as RSV bronchiolitis is associated with an increased risk of asthma, morbidity, and reduced lung function in this Latino population.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB178-AB178
Main Authors: Rajesh, Kumar, MD, MS, FAAAAI, Cho, Seong Ho, MD, FAAAAI, Min, Jin Young, MD, PhD, Kang, Joseph, PhD, Chan, Wendy, MEd, Kim, Dong-Young, Oh, Sam, PhD, MPH, Torgerson, Dara, PhD, Del-Pino-Yanes, Maria del Mar, MD, Hu, Donglei, PhD, Sen, Saunak, PhD, Huntsman, Scott, MS, Eng, Celeste, BS, Farber, Harold J., MD, MSPH, Rodriguez-Cintron, William, Rodriguez-Santana, Jose, MD, Serebrisky, Denise, MD, Thyne, Shannon, MD, Borrell, Luisa, DDS, PhD, Williams, L. Keoki, MD, MPH, FAAAAI, Seibold, Max, PhD, Burchard, Esteban Gonzalez, MD, MPH, Avila, Pedro C., MD
Format: Article
Language:English
Subjects:
Allergy and Immunology
Asthma
Infections
Respiratory diseases
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Description
Summary:Conclusions A genetic variant of PAI-1 together with early life LRI such as RSV bronchiolitis is associated with an increased risk of asthma, morbidity, and reduced lung function in this Latino population.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.717