Morpholine Catalyzed One-pot Multicomponent Synthesis of Compounds Containing Chromene Core in Water

A series of dihydropyrano[c]chromene was obtained via condensation of aldehyde, malononitrile and 4-hydroxycoumarin in water catalyzed by morpholine, as a one-pot reaction. The significance of our findings relates to reducing the use of organic solvents, potentially toxic and hazardous materials, as...

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Bibliographic Details
Published in:Chinese journal of chemistry 2011-06, Vol.29 (6), p.1163-1166
Main Author: Heravi, Majid M. Zakeri, Masoumeh Mohammadi, Narges
Format: Article
Language:English
Subjects:
dihydropyrano[c]chromene
morpholine
multicomponent
organocatalysis
二氢吡喃
催化缩合
化合物
合成
吗啉
多组分
有毒有害物质
水
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Summary:A series of dihydropyrano[c]chromene was obtained via condensation of aldehyde, malononitrile and 4-hydroxycoumarin in water catalyzed by morpholine, as a one-pot reaction. The significance of our findings relates to reducing the use of organic solvents, potentially toxic and hazardous materials, as well as its simplicity, good yields, mild conditions, and lower costs.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201190217