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Copper-catalyzed N-Arylation of Imidazoles with Aryl or Heteroaryl Halides Facilitated by Dimethylglyoxime in Water

A combination of CuSO4/dimethylglyoxime was found to be an efficient and inexpensive catalyst system for N-arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.

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Bibliographic Details
Published in:Chinese journal of chemistry 2011-10, Vol.29 (10), p.2124-2128
Main Author: 吴香梅 胡卫雅
Format: Article
Language:English
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Summary:A combination of CuSO4/dimethylglyoxime was found to be an efficient and inexpensive catalyst system for N-arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201180368