Combustion Derived Nanocrystalline-ZrO2 and Its Catalytic Activity for Biginelli Condensation under Microwave Irradiation

• Published in: Chinese journal of chemistry 2011-09, Vol.29 (9), p.1863-1868
• Main Author: Bhojegowd, Madhusudana Reddy M. Siddaramanna, Ashoka Siddappa, Anandakumar B. Thimmanna, Chandrappa G. Pasha, Mohamed A
• Format: Article
• Language: English
• Subjects: 3,4‐dihydropyrimidinones; 4-dihydropyrimidinones; araldehydes; Biginelli缩合; catalysis; Condensation; ethylaceto acetate; green chemistry; nano materials; nanocrystalline-ZrO2; solution combustion; 催化活性; 微波辐射; 无溶剂合成; 燃烧方法; 粉末X射线衍射; 纳米ZrO2; 纳米氧化锆
• ISSN: 1001-604X; 1614-7065
• DOI: 10.1002/cjoc.201180325

Nanocrystalline zirconium（IV） oxide （nc-ZrO2） possessing high surface area was synthesized by a low tem- perature eco-friendly solution combustion method using a new organic fuel alanine. The powder XRD, SEM and surface area measurements were carried out for characterization of nc-ZrO2. The powder XRD results revealed that, the nc-ZrO2 has the pure tetragonal phase. The crystallite size calculated by Scherrer＇s formula and BET surface area were found to be ca. 53--57 nm and ca. 275 m2/g, respectively. SEM micrograph exhibited the macroporous nature of the powder, nc-ZrO2 has been employed as a catalyst for the solvent-free synthesis of 3,4-dihydro- pyrimidin-2-ones （DHPMs） by a microwave （MW） assisted one-pot, multicomponent Biginelli condensation reaction of araldehydes, ethylacetoacetate and urea or thiourea. DHPMs are obtained in good to excellent yields （85%-- 96%） under this reaction condition within short interval of time （10--20 min）.